Article
IFT-81 and IFT-74 are required for intraflagellar transport in C. elegans.
Genes to cells : devoted to molecular & cellular mechanisms - 1 May 2007
Kobayashi Tetsuo, Gengyo-Ando Keiko, Ishihara Takeshi, Katsura Isao, Mitani Shohei
Abstract excerpt
Intraflagellar transport (IFT) is essential machinery for biogenesis and maintenance of cilia in many eukaryotic and prokaryotic cells. A large number of polypeptides are known to be involved in IFT, but the physiological role of each component is not fully elucidated. Here, we identified a C. elegans orthologue of a Chlamydomonas reinhardtii IFT component, IFT-81, and found that its loss-of-function mutants show...
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