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Article

Distinct IFT mechanisms contribute to the generation of ciliary structural diversity in C. elegans.

The EMBO journal - 20 Jun 2007

Mukhopadhyay Saikat, Lu Yun, Qin Hongmin, Lanjuin Anne, Shaham Shai, Sengupta Piali

Abstract excerpt

Individual cell types can elaborate morphologically diverse cilia. Cilia are assembled via intraflagellar transport (IFT) of ciliary precursors; however, the mechanisms that generate ciliary diversity are unknown. Here, we examine IFT in the structurally distinct cilia of the ASH/ASI and the AWB chemosensory neurons in Caenorhabditis elegans, enabling us to compare IFT in specific cilia types. We show that unlike...

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PMID: 17510633
DOI: 10.1038/sj.emboj.7601717
PMCID: PMC1894762

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