Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of Escherichia coli for growth at high temperatures.

The Journal of biological chemistry - 18 Jun 2010

Rudolph Birgit, Gebendorfer Katharina M, Buchner Johannes, Winter Jeannette

Abstract excerpt

Evolution depends on the acquisition of genomic mutations that increase cellular fitness. Here, we evolved Escherichia coli MG1655 cells to grow at extreme temperatures. We obtained a maximum growth temperature of 48.5 degrees C, which was not increased further upon continuous cultivation at this temperature for >600 generations. Despite a permanently induced heat shock response in thermoresistant cells, only...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hot Temperature
Share to Proteomics
Share to Chaperonin 10

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chaperonin 60

Share to Chaperonins

Share to Electrophoresis, Gel, Two-Dimensional

Share to Escherichia coli Proteins

Share to Heat-Shock Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20406805
DOI: 10.1074/jbc.M110.103374
PMCID: PMC2885180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of Escherichia coli for growth at high temperatures.PMID 20406805Read ↗

Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness.Semantic proximity Read ↗

Laboratory Evolution Reveals Transcriptional Mechanisms Underlying Thermal Adaptation of Escherichia coli.Semantic proximity Read ↗

Evolution of Escherichia coli to 42 °C and subsequent genetic engineering reveals adaptive mechanisms and novel mutations.Semantic proximity Read ↗

Enhancing the heat tolerance of homolactic Escherichia coli through reverse metabolic engineering.Semantic proximity Read ↗

Experimental evolution of a facultative thermophile from a mesophilic ancestor.Semantic proximity Read ↗

Sequence analysis and phenotypic characterization of groEL mutations that block lambda and T4 bacteriophage growth.Semantic proximity Read ↗

Physiological roles of the DnaK and GroE stress proteins: catalysts of protein folding or macromolecular sponges?Semantic proximity Read ↗

Functional Analysis of Genes Comprising the Locus of Heat Resistance in Escherichia coliSemantic proximity Read ↗

Genetic Mutations That Drive Evolutionary Rescue to Lethal Temperature in Escherichia coli.Semantic proximity Read ↗

The hallmarks of a tradeoff in transcriptomes that balances stress and growth functions.Semantic proximity Read ↗

A small heat shock protein enables Escherichia coli to grow at a lethal temperature of 50°C conceivably by maintaining cell envelope integrity.Semantic proximity Read ↗

A grpE mutant of Escherichia coli is more resistant to heat than the wild-type.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.