Article
A small heat shock protein enables Escherichia coli to grow at a lethal temperature of 50°C conceivably by maintaining cell envelope integrity.
Journal of bacteriology - 1 Jun 2014
Ezemaduka Anastasia N, Yu Jiayu, Shi Xiaodong, Zhang Kaiming, Yin Chang-Cheng, Fu Xinmiao, Chang Zengyi
Abstract excerpt
It is essential for organisms to adapt to fluctuating growth temperatures. Escherichia coli, a model bacterium commonly used in research and industry, has been reported to grow at a temperature lower than 46.5°C. Here we report that the heterologous expression of the 17-kDa small heat shock protein from the nematode Caenorhabditis elegans, CeHSP17, enables E. coli cells to grow at 50°C, which is their highest...
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