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Article

Ras mutations in United Kingdom examples of oral malignancies are infrequent.

International journal of cancer - 30 May 1991

Chang S E, Bhatia P, Johnson N W, Morgan P R, McCormick F, Young B, Hiorns L

Abstract excerpt

Point mutations in codons 12, 13 or 61 of the oncogenes Ha-ras, Ki-ras or N-ras have been identified in human malignancies of many types. Using the PCR (polymerase chain reaction) technique for DNA amplification in vitro and stringent probing of the amplified DNA on dot blots with a library of specific oligonucleotides, we have screened for the presence of ras mutations in oral and para-oral malignancies and some...

Topics

Aged
Codon
DNA, Neoplasm
Female
Genes, ras
Humans
Male
Middle Aged
Mouth Neoplasms
Mutation
Oligonucleotide Probes
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

United Kingdom

Source

Identifiers

PMID: 2040536
DOI: 10.1002/ijc.2910480318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2040536-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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