N-ras 61 oncogene mutations in Hürthle cell tumors.

Article

N-ras 61 oncogene mutations in Hürthle cell tumors.

Surgery - 1 Dec 1990

Schark C, Fulton N, Jacoby R F, Westbrook C A, Straus F H, Kaplan E L

Abstract excerpt

Mutations of ras oncogenes are believed to play an important role in the initiation or progression of human tumors. In thyroid tumors the incidence of ras activation by specific point mutations has been reported to range from 33% in follicular adenomas up to 60% in anaplastic carcinomas. Because...

Topics

Adenoma
Adult
Base Sequence
Genes, ras
Humans
Lung Neoplasms
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Survival Analysis
Thyroid Neoplasms

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