Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

N-ras 61 oncogene mutations in Hürthle cell tumors.

Surgery - 1 Dec 1990

Schark C, Fulton N, Jacoby R F, Westbrook C A, Straus F H, Kaplan E L

Abstract excerpt

Mutations of ras oncogenes are believed to play an important role in the initiation or progression of human tumors. In thyroid tumors the incidence of ras activation by specific point mutations has been reported to range from 33% in follicular adenomas up to 60% in anaplastic carcinomas. Because of our long-standing interest in Hürthle cell tumors, we began a study of 70 such cases to determine the incidence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Base Sequence
Share to Genes, ras

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Share to Survival Analysis

Source

Identifiers

PMID: 2247846

Genes

CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

N-ras 61 oncogene mutations in Hürthle cell tumors.PMID 2247846Read ↗

Ras oncogene mutations in benign and malignant thyroid neoplasms.Semantic proximity Read ↗

Point mutations of ras oncogenes are an early event in thyroid tumorigenesis.Semantic proximity Read ↗

The associations between RAS mutations and clinical characteristics in follicular thyroid tumors: new insights from a single center and a large patient cohort.Semantic proximity Read ↗

Prevalence of Ras mutations in thyroid neoplasia.Semantic proximity Read ↗

<i>RAS</i>Point Mutations and PAX8-PPARγ Rearrangement in Thyroid Tumors: Evidence for Distinct Molecular Pathways in Thyroid Follicular CarcinomaSemantic proximity Read ↗

Low frequency of ras gene mutations in neuroblastomas, pheochromocytomas, and medullary thyroid cancers.Semantic proximity Read ↗

Prevalence of activating ras mutations in morphologically characterized thyroid nodules.Semantic proximity Read ↗

N-ras mutation of thyroid tumor with special reference to the follicular type.Semantic proximity Read ↗

N- <i>ras</i> Mutation in Poorly Differentiated Thyroid Carcinomas: Correlation with Bone Metastases and Inverse Correlation to Thyroglobulin ExpressionSemantic proximity Read ↗

The value of measurement of ras oncogenes and nuclear DNA analysis in the diagnosis of Hürthle cell tumors of the thyroid.Semantic proximity Read ↗

Molecular genetic study comparing follicular variant versus classic papillary thyroid carcinomas: association of N-ras mutation in codon 61 with follicular variant.Semantic proximity Read ↗

High rates of ras codon 61 mutation in thyroid tumors in an iodide-deficient area.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.