Article
CenH3/CID incorporation is not dependent on the chromatin assembly factor CHD1 in Drosophila.
PloS one - 9 Apr 2010
Podhraski Valerie, Campo-Fernandez Beatriz, Wörle Hildegard, Piatti Paolo, Niederegger Harald, Böck Günther, Fyodorov Dmitry V, Lusser Alexandra
Abstract excerpt
CHD1 is a SNF2-related ATPase that is required for the genome-wide incorporation of variant histone H3.3 in the paternal pronucleus as well as in transcriptionally active nuclei in Drosophila embryos. The S. pombe and vertebrate orthologs of CHD1 have been implicated in the assembly of the centromeric histone H3 variant CenH3(CENP-A), which occurs in a DNA replication-independent manner. Here, we examined whether...
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