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Article

Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians.

Diabetologia - 1 Jul 2010

Bian L, Hanson R L, Muller Y L, Ma L, Kobes S, Knowler W C, Bogardus C, Baier L J

Abstract excerpt

AIMS/HYPOTHESIS: A prior genome-wide association study in Pima Indians identified a variant within the ACAD10 gene that is associated with early-onset type 2 diabetes. Acylcoenzyme A dehydrogenase 10 (ACAD10) catalyses mitochondrial fatty acid beta-oxidation, which plays a pivotal role in developing insulin resistance and type 2 diabetes. Therefore, ACAD10 was analysed as a positional and biological candidate for...

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Share to Acyl-CoA Dehydrogenase
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Indians, North American

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Source

Open in PubMed Open full text

Identifiers

PMID: 20390405
DOI: 10.1007/s00125-010-1695-y
PMCID: PMC2947857

Genes

ACAD10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians.PMID 20390405Read ↗

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