Article
Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians.
Diabetologia - 1 Mar 2016
Nair Anup K, Piaggi Paolo, McLean Nellie A, Kaur Manmeet, Kobes Sayuko, Knowler William C, Bogardus Clifton, Hanson Robert L, Baier Leslie J
Abstract excerpt
AIMS/HYPOTHESIS: Epidemiological studies in Pima Indians identified elevated levels of HDL-cholesterol (HDL-C) as a protective factor against type 2 diabetes risk in women. We assessed whether HDL-C-associated single-nucleotide polymorphisms (SNPs) also associate with type 2 diabetes in female Pima Indians. METHODS: Twenty-one SNPs in established HDL-C loci were initially analysed in 2,675 full-heritage Pima...
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