Article
Lack of effect of compartmentalized drug resistance mutations on HIV-1 pol divergence in antiretroviral-experienced women.
AIDS (London, England) - 1 Jun 2010
Kelley Colleen F, Sullivan Sharon T, Lennox Jeffrey L, Evans-Strickfaden Tammy, Hart Clyde E
Abstract excerpt
OBJECTIVE: To examine the persistence of compartmentalized HIV drug resistance mutations (DRM) over time in the female genital tract and its effect on pol gene divergence compared to that in blood. DESIGN: Longitudinal cohort of 22 antiretroviral-experienced women in the Emory Vaginal Ecology study. METHODS: Blood and vaginal secretions were collected at serial clinic visits. DRM in the HIV reverse transcriptase...
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