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Article

Correlating familial Alzheimer's disease gene mutations with clinical phenotype.

Biomarkers in medicine - 1 Feb 2010

Ryan Natalie S, Rossor Martin N

Abstract excerpt

Alzheimer's disease (AD) causes devastating cognitive impairment and an intense research effort is currently devoted to developing improved treatments for it. A minority of cases occur at a particularly young age and are caused by autosomal dominantly inherited genetic mutations. Although rare, familial AD provides unique opportunities to gain insights into the cascade of pathological events and how they relate...

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Identifiers

PMID: 20387306
DOI: 10.2217/bmm.09.92
PMCID: PMC3937872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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