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Article

Deciphering the genetic basis of Alzheimer's disease.

Annual review of genomics and human genetics - 1 Jan 2002

Selkoe Dennis J, Podlisny Marcia B

Abstract excerpt

A remarkable rise in life expectancy during the past century has made Alzheimer's disease (AD) the most common form of progressive cognitive failure in humans. Compositional analyses of the classical brain lesions, the senile (amyloid) plaques and neurofibrillary tangles, preceded and has guided the search for genetic alterations. Four genes have been unequivocally implicated in inherited forms of AD, and...

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Identifiers

PMID: 12142353
DOI: 10.1146/annurev.genom.3.022502.103022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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