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New Insights into the Molecular Bases of Familial Alzheimer’s Disease

19 Apr 2020

Abstract excerpt

Like several neurodegenerative disorders, such as Prion and Parkinson diseases, Alzheimer’s disease (AD) is characterized by spreading mechanism of aggregated proteins in the brain in a typical “prion-like” manner. Recent genetic studies have identified in four genes associated with inherited AD (amyloid precursor protein-APP, Presenilin-1, Presenilin-2 and Apolipoprotein E), rare mutations which cause...

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PMID: 32325882
DOI: 10.3390/jpm10020026

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