Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genes associated with Alzheimer's disease: an overview and current status.

Clinical interventions in aging - 1 Jan 2016

Giri Mohan, Zhang Man, Lü Yang

Abstract excerpt

Alzheimer's disease (AD) is a progressive, neurodegenerative disease and the most common form of dementia in elderly people. It is an emerging public health problem that poses a huge societal burden. Linkage analysis was the first milestone in unraveling the mutations in APP, PSEN1, and PSEN2 that cause early-onset AD, followed by the discovery of apolipoprotein E-ε4 allele as the only one genetic risk factor for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Protein Precursor
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Presenilin-1

Share to Presenilin-2

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 27274215
DOI: 10.2147/CIA.S105769
PMCID: PMC4876682

Genes

ADAM10
AKAP9
APP
PLD3
PSEN1
PSEN2
TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genes associated with Alzheimer's disease: an overview and current status.PMID 27274215Read ↗

Genomic variants, genes, and pathways of Alzheimer's disease: An overview.Semantic proximity Read ↗

The current status of Alzheimer's disease genetics: what do we tell the patients?Semantic proximity Read ↗

The genetics of Alzheimer disease: back to the future.Semantic proximity Read ↗

Molecular genetics of Alzheimer's disease: an update.Semantic proximity Read ↗

Common and Rare Genetic Variants Associated With Alzheimer's Disease.Semantic proximity Read ↗

State of Play in Alzheimer’s Disease GeneticsSemantic proximity Read ↗

Alzheimer's disease genetics: from the bench to the clinic.Semantic proximity Read ↗

Genetics of Alzheimer Disease.Semantic proximity Read ↗

The genetics of Alzheimer disease.Semantic proximity Read ↗

Genomics and Functional Genomics of Alzheimer's Disease.Semantic proximity Read ↗

Genomics of Alzheimer's disease: Value of high-throughput genomic technologies to dissect its etiology.Semantic proximity Read ↗

Alzheimer's disease risk genes and mechanisms of disease pathogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.