Article
Genetics of Alzheimer disease.
Journal of geriatric psychiatry and neurology - 1 Dec 2010
Bekris Lynn M, Yu Chang-En, Bird Thomas D, Tsuang Debby W
Abstract excerpt
Alzheimer disease (AD) is the most common causes of neurodegenerative disorder in the elderly individuals. Clinically, patients initially present with short-term memory loss, subsequently followed by executive dysfunction, confusion, agitation, and behavioral disturbances. Three causative genes have been associated with autosomal dominant familial AD (APP, PSEN1, and PSEN2) and 1 genetic risk factor (APOEε4...
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