Clinical features of sporadic and familial Alzheimer's disease.

doi:10.1006/neur.1996.0052

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Article

Clinical features of sporadic and familial Alzheimer's disease.

Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration - 1 Dec 1996

Rossor M N, Fox N C, Freeborough P A, Harvey R J

Abstract excerpt

Alzheimer's disease is increasingly seen as an heterogeneous disorder with a variety of molecular pathologies converging on a final common pathway of abnormal amyloid deposition and tau phosphorylation. These result in the appearance of the senile plaques and neurofibrillary tangles and in the su...

Topics

Alzheimer Disease
Humans
Longitudinal Studies
Mutation
Nervous System

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