Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers.

Human genetics - 1 Jun 2010

Wei Jinxue, Ma Jennie Z, Payne Thomas J, Cui Wenyan, Ray Riju, Mitra Nandita, Lerman Caryn, Li Ming D

Abstract excerpt

Choline acetyltransferase is critical in the synthesis of acetylcholine and regulation of cholinergic neuron functions. We recently reported association of the encoding gene ChAT with both smoking cessation and nicotine dependence (ND) in two independent European American (EA) samples; however, in the replication sample, only limited SNPs partially covering the gene were examined. In this study, we examined the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Choline O-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family

Share to Haplotypes

Share to Smoking

Share to Smoking Cessation

Share to Tobacco Use Disorder

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 20383528
DOI: 10.1007/s00439-010-0818-3
PMCID: PMC5574174

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers.PMID 20383528Read ↗

Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence.Semantic proximity Read ↗

Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence.Semantic proximity Read ↗

Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence.Semantic proximity Read ↗

Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers.Semantic proximity Read ↗

Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations.Semantic proximity Read ↗

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.Semantic proximity Read ↗

Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population.Semantic proximity Read ↗

Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence.Semantic proximity Read ↗

Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population.Semantic proximity Read ↗

Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.Semantic proximity Read ↗

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.Semantic proximity Read ↗

Possible association of nicotinic acetylcholine receptor gene (CHRNA4 and CHRNB2) polymorphisms with nicotine dependence in Japanese males: an exploratory study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.