Article
Possible association of nicotinic acetylcholine receptor gene (CHRNA4 and CHRNB2) polymorphisms with nicotine dependence in Japanese males: an exploratory study.
Pharmacopsychiatry - 1 Mar 2013
Chen H-I, Shinkai T, Utsunomiya K, Yamada K, Sakata S, Fukunaka Y, Hwang R, De Luca V, Ohmori O, Kennedy J L, Chuang H-Y, Nakamura J
Abstract excerpt
INTRODUCTION: Smoking is a leading global cause of avoidable mortality. It has been reported that the nicotinic acetylcholine receptor (CHRNA4 and CHRNB2) genes might be associated with smoking behavior in several ethnic populations. However, no study between the 2 genes and nicotine dependence (ND) using a Japanese population has been reported. METHODS: We examined the association between ND and 5 single...
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