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Article

LRP1B: A Giant Lost in Cancer Translation

24 Aug 2021

Abstract excerpt

Low-density lipoprotein receptor-related protein 1B (LRP1B) is a giant member of the LDLR protein family, which includes several structurally homologous cell surface receptors with a wide range of biological functions from cargo transport to cell signaling. LRP1B is among the most altered genes in human cancer overall. Found frequently inactivated by several genetic and epigenetic mechanisms, it has mostly been...

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PMID: 34577535
DOI: 10.3390/ph14090836

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