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Article

NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn's disease.

World journal of gastroenterology - 14 Apr 2010

Gazouli Maria, Pachoula Ioanna, Panayotou Ioanna, Mantzaris Gerassimos, Chrousos George, Anagnou Nicholas P, Roma-Giannikou Eleftheria

Abstract excerpt

AIM: To assess whether the polymorphisms of NOD2/CARD15, autophagy-related 16-like 1 (ATG16L1), and interleukin-23 receptor (IL23R) genes play a more critical role in the susceptibility of childhood-onset than in adult-onset Crohn's disease (CD). METHODS: Polymorphisms R702W, G908R, and 3020insC of NOD2/CARD15; rs2241880 A/G of ATG16L1, and rs11209026 (R381Q) of IL23R gene were assessed in 110 childhood-onset CD,...

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Source

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Identifiers

PMID: 20380008
DOI: 10.3748/wjg.v16.i14.1753
PMCID: PMC2852824

Genes

NOD2

Variants

rs2241880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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