Article
NOD2 sequencing in Iranian children with Crohn's disease.
Zeitschrift fur Gastroenterologie - 1 Jul 2011
Motamed F, Najafi M, Taghvaei M, Moazzami K, Farahmand F, Khodadad A, Fallahi G-H, Parvaneh N, Khatami G-R, Rezaei N
Abstract excerpt
Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Although the exact etiology of disease is still unknown, mutations in the CARD15/NOD2 gene have been reported in association with CD in several studies. This study was performed to determine whether the CARD15/NOD2 gene confers susceptibility to Iranian pediatric patients with CD. All 12 coding exons of the CARD15/NOD2 gene were...
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