Article
Genetic susceptibility has a more important role in pediatric-onset Crohn's disease than in adult-onset Crohn's disease.
Inflammatory bowel diseases - 1 Sept 2007
de Ridder Lissy, Weersma Rinse K, Dijkstra Gerard, van der Steege Gerrit, Benninga Marc A, Nolte Ilja M, Taminiau Jan A J M, Hommes Daniël W, Stokkers Pieter C F
Abstract excerpt
BACKGROUND: Genetic susceptibility may play a more important role in the etiology of early-onset inflammatory bowel disease (IBD) than in late-onset IBD, and therefore pediatric-onset IBD patients can be expected to have a higher frequency of gene mutations. We aimed to determine genotypes and phenotypes of patients with pediatric-onset IBD, to compare them with those of patients with adult-onset IBD and with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.