Article
IL23R, NOD2/CARD15, ATG16L1 and PHOX2B polymorphisms in a group of patients with Crohn's disease and correlation with sub-phenotypes.
International journal of molecular medicine - 1 Mar 2011
Lauriola Mattia, Ugolini Giampaolo, Rivetti Stefano, Nanì Sara, Rosati Giancarlo, Zanotti Simone, Montroni Isacco, Manaresi Alessio, Zattoni Davide, Belluzzi Andrea, Castellani Lucia, D'Uva Gabriele, Mattei Gabriella, Taffurelli Mario, Strippoli Pierluigi, Solmi Rossella
Abstract excerpt
Recent genomic research has identified interleukin-23 receptor (IL23R), nucleotide-binding oligomerization domain containing 2 caspase-activation recruitment domain 15 (NOD2/CARD15), autophagy related 16-like 1 (ATG16L1) and paired-like homeobox 2b (PHOX2B) as susceptibility loci for Crohn's Disease (CD). Our aim was to investigate these gene variants in a group of CD patients and to analyse the correlation to...
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