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Article

NOD2/CARD15 and TNFA, but not IL1B and IL1RN, are associated with Crohn's disease.

Inflammatory bowel diseases - 1 Apr 2005

Ferreira António Carlos, Almeida Susana, Tavares Marta, Canedo Paulo, Pereira Fábio, Regalo Gonçalo, Figueiredo Céu, Trindade Eunice, Seruca Raquel, Carneiro Fátima, Amil Jorge, Machado José Carlos, Tavarela-Veloso Fernando

Abstract excerpt

BACKGROUND: NOD2/CARD15 was described as the first susceptibility gene to Crohn's disease (CD). Polymorphisms in the TNFA gene and in the IL1 gene cluster, which are associated with an enhanced chronic inflammatory response, may also play a role in the development of CD. The aim of this study was to determine the association of polymorphisms in the CARD15, TNFA, IL1B, and IL1RN genes with risk of development of...

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Identifiers

PMID: 15803022
DOI: 10.1097/01.mib.0000158153.71579.b4

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NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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NOD2/CARD15 and TNFA, but not IL1B and IL1RN, are associated with Crohn's disease.PMID 15803022Read ↗

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