Article
GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients.
Clinical and experimental pharmacology & physiology - 1 Aug 2010
Polimanti Renato, Piacentini Sara, Moscatelli Barbara, Pellicciotti Luisa, Manfellotto Dario, Fuciarelli Maria
Abstract excerpt
1. Previous studies have established that genetic alterations in glutathione S-transferase enzymes may change the ability of the airway to deal with toxic substances and increase the risk of asthma. The present study analysed the association between asthma and GSTA1, GSTO1 and GSTO2 gene polymorphisms. 2. The GSTA1*-69C/T, GSTO1*A140D and GSTO2*N142D polymorphisms were detected by polymerase chain...
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