Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic alterations of glutathione S-transferases in asthma: do they modulate lung growth and response to environmental stimuli?

Allergy and asthma proceedings - 1 Jan 2000

Sampsonas Fotis, Archontidou Maria-Antigoni, Salla Eugenia, Karkoulias Kiriakos, Tsoukalas George, Spiropoulos Kostas

Abstract excerpt

Glutathione S-transferases (GSTs) constitute a super family of dimeric phase II metabolic enzymes that catalyze the conjugation of reduced glutathione with various electrophilic compounds and reactive oxygen species (ROS). Failure to detoxify ROS, as a sequel of altered GST genotype is able to aggravate the inflammatory cascade, promote bronchoconstrictor mechanisms, activate asthma-like symptomatology, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Asthma

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glutathione Transferase

Source

Identifiers

PMID: 17619555
DOI: 10.2500/aap.2007.28.3002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic alterations of glutathione S-transferases in asthma: do they modulate lung growth and response to environmental stimuli?PMID 17619555Read ↗

Glutathione S-Transferase Gene Associations and Gene-Environment Interactions for Asthma.Semantic proximity Read ↗

Polymorphisms at the glutathione S-transferase, GSTP1 locus: a novel mechanism for susceptibility and development of atopic airway inflammation.Semantic proximity Read ↗

Impact of glutathione-S-transferase gene polymorphisms on enzyme activity, lung function and bronchial asthma susceptibility in Egyptian children.Semantic proximity Read ↗

Molecular Approach of Oxidative Stress and Bronchopulmonary Dysplasia: Relationship of GSTM1 and GSTT1 Genes.Semantic proximity Read ↗

Glutathione-S-transferase genes and asthma phenotypes: a Human Genome Epidemiology (HuGE) systematic review and meta-analysis including unpublished data.Semantic proximity Read ↗

Glutathione-S-transferase gene polymorphisms (GSTT1, GSTM1, GSTP1) as increased risk factors for asthma.Semantic proximity Read ↗

Glutathione S-transferase gene polymorphism and asthma: a case-control study in a pediatric population.Semantic proximity Read ↗

Glutathione S-transferase polymorphisms, asthma susceptibility and confounding variables: a meta-analysis.Semantic proximity Read ↗

Glutathione S-transferase: genetics and role in toxicology.Semantic proximity Read ↗

Air pollution associated acute respiratory inflammation and modification by GSTM1 and GSTT1 gene polymorphisms: a panel study of healthy undergraduates.Semantic proximity Read ↗

The Association between Gene-Environment Interactions and Diseases Involving the Human GST Superfamily with SNP Variants.Semantic proximity Read ↗

[Genetic and biochemical mechanisms of involvement of antioxidant defense enzymes in the development of bronchial asthma].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.