Article
Functional polymorphisms of GSTA1 and GSTO2 genes associated with asthma in Italian children.
Clinical chemistry and laboratory medicine - 31 Oct 2011
Piacentini Sara, Verrotti Alberto, Polimanti Renato, Giannini Cosimo, Saccucci Patrizia, Manfellotto Dario, Fuciarelli Maria
Abstract excerpt
BACKGROUND: Asthma is an airway disorder characterized by bronchial inflammation. An imbalance between the oxidative forces and the antioxidant defense systems has been implicated in the pathogenesis of asthma. Glutathione S-transferases (GSTs) play an important role in cellular protection agains...
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