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Article

Functional polymorphisms of GSTA1 and GSTO2 genes associated with asthma in Italian children.

Clinical chemistry and laboratory medicine - 31 Oct 2011

Piacentini Sara, Verrotti Alberto, Polimanti Renato, Giannini Cosimo, Saccucci Patrizia, Manfellotto Dario, Fuciarelli Maria

Abstract excerpt

BACKGROUND: Asthma is an airway disorder characterized by bronchial inflammation. An imbalance between the oxidative forces and the antioxidant defense systems has been implicated in the pathogenesis of asthma. Glutathione S-transferases (GSTs) play an important role in cellular protection against inflammation. Several studies have investigated the genetic variability of GSTM1, GSTP1 and GSTT1 enzymes in asthma...

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Source

Identifiers

PMID: 22040239
DOI: 10.1515/CCLM.2011.774

Genes

GSTA1
GSTO2
GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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