Article
Lack of association between GSTM1, GSTP1, and GSTT1 gene polymorphisms and asthma in adult patients from Rome, central Italy.
Journal of investigational allergology & clinical immunology - 1 Jan 2012
Piacentini S, Polimanti R, Moscatelli B, Re M A, Manfellotto D, Fuciarelli M
Abstract excerpt
BACKGROUND: Asthma is a complex multifactorial disease that is not yet fully understood. Oxidative stress due to an imbalance between the oxidative forces and the antioxidant defense systems has been implicated in asthma pathogenesis. However, much debate still surrounds the key genetic factors involved in the development of this disease. Candidate genes include the glutathione S-transferases (GSTs). In...
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