Article
Glutathione-S-transferase gene polymorphisms (GSTT1, GSTM1, GSTP1) as increased risk factors for asthma.
Respirology (Carlton, Vic.) - 1 Nov 2004
Tamer Lülüfer, Calikoğlu Mukadder, Ates Nurcan Aras, Yildirim Hatice, Ercan Bahadir, Saritas Emel, Unlü Ali, Atik Ugur
Abstract excerpt
OBJECTIVES: Asthma is a complex multifactorial disease with an obvious genetic predisposition, immunological aberration, and involvement of noxious environmental factors. Polymorphisms of the glutathione-S-transferase (GST) genes are known risk factors for some environmentally-related diseases. In the present study, the hypothesis that polymorphisms in the GSTT1, GSTM1 and GSTP1 genes are associated with atopic...
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