Article
Glutathione- S-transferase micro and theta gene polymorphisms as new risk factors of atopic bronchial asthma.
Journal of molecular medicine (Berlin, Germany) - 1 Jan 2002
Ivaschenko T E, Sideleva O G, Baranov V S
Abstract excerpt
The genetic polymorphism of glutathione- S-transferase M1 (GSTM1) and glutathione- S-transferase T1 (GSTT1) genes and the cytochrome P4501A1 gene responsible for xenobiotic conjugating enzymes of the phase II and phase I detoxification system were studied by PCR-RFLP in the blood spots of 109 patients with atopic bronchial asthma and 90 healthy individuals. GSTM1 gene deletion (GSTM1(0/0)) was detected in 47.8%...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
