Article
Glutathione S-transferase gene polymorphism and asthma: a case-control study in a pediatric population.
Pharmacogenomics - 1 May 2022
Kumar Ankit, Ahmed Tanzeel, Parvez Mohammad K, Banerjee Basu Dev, Maqusood Mazher, Jagirdar Rajesh M
Abstract excerpt
Aim: To carry out a case-control study of the association of GST gene polymorphisms in pediatric asthma-related oxidative stress. Materials & methods: Asthma patients (n = 250) and age-matched healthy subjects (n = 250) DNA were genotyped for GSTM1/GSTT1 (+/+, +/-, -/+ and -/-) frequencies using multiplex-PCR and plasma oxidative stress markers (examined spectrophotometrically). Results: Asthma patients had...
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