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Article

Glutathione S-transferase polymorphisms, asthma susceptibility and confounding variables: a meta-analysis.

Molecular biology reports - 1 Apr 2013

Piacentini Sara, Polimanti Renato, Simonelli Ilaria, Donno Silvia, Pasqualetti Patrizio, Manfellotto Dario, Fuciarelli Maria

Abstract excerpt

Oxidative stress is one of the main risk factors for asthma development. Glutathione S-transferases play an important role in antioxidant defences and may influence asthma susceptibility. In particular, GSTM1 and GSTT1 positive/null genotypes and the GSTP1 Ile105 Val polymorphism have been analyzed in a number of genetic association studies, with conflicting outcomes. Two previous meta-analyses have attempted to...

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Source

Identifiers

PMID: 23307299
DOI: 10.1007/s11033-012-2405-2

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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