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Article

Neuregulin 1-induced AKT phosphorylation in monozygotic twins discordant for schizophrenia.

Neurochemistry international - 1 Jul 2010

Seres Imola, Kelemen Oguz, Benedek György, Kéri Szabolcs

Abstract excerpt

Patients with schizophrenia exhibit decreased neuregulin 1 (NRG1)-stimulated AKT phosphorylation in peripheral lymphoblasts. Here, we examined this peripheral marker in monozygotic twins discordant for schizophrenia and in healthy monozygotic twins without psychiatric disorders. B lymphoblasts were stimulated with NRG1a (65 amino-acid residue recombinant protein from the epidermal growth factor [EGF] domain) for...

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Source

Identifiers

PMID: 20371257
DOI: 10.1016/j.neuint.2010.03.018

Genes

NRG1
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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