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Peripheral Transcription of NRG-ErbB Pathway Genes Are Upregulated in Treatment-Resistant Schizophrenia

6 Nov 2017

Abstract excerpt

Investigation of peripheral gene expression patterns of transcripts within the NRG-ErbB signaling pathway, other than neuregulin-1 (NRG1), among patients with schizophrenia and more specifically treatment-resistant schizophrenia (TRS) is limited. The present study built on our previous work demonstrating elevated levels of NRG1 EGFα, EGFβ and type I(Ig2) containing transcripts in TRS by investigating 11 NRG-ErbB...

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PMID: 29163244
DOI: 10.3389/fpsyt.2017.00225

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