Article
Corticomotoneuronal function in asymptomatic SOD-1 mutation carriers.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology - 1 Oct 2010
Vucic Steve, Winhammar Jennica M C, Rowe Dominic B, Kiernan Matthew C
Abstract excerpt
OBJECTIVE: Diffusion tensor imaging (DTI) recently identified structural abnormalities of corticomotoneurons in asymptomatic copper/zinc superoxide-dismutase-1 (SOD-1) gene mutation carriers. The potential existence of longstanding corticomotoneuronal dysfunction would clearly have consequences for the medical management of asymptomatic SOD-1 mutation carriers. To clarify this unexpected finding, DTI techniques...
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