Article
Abnormal corticospinal tract function and motor cortex excitability in non-ataxic SCA2 mutation carriers: A TMS study.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology - 1 Aug 2016
Velázquez-Pérez Luis, Rodríguez-Labrada Roberto, Torres-Vega Reidenis, Medrano Montero Jacqueline, Vázquez-Mojena Yaimeé, Auburger Georg, Ziemann Ulf
Abstract excerpt
OBJECTIVE: To evaluate if the corticospinal tract is affected in the prodromal stage of spinocerebellar ataxia type 2 (SCA2), prior to development of the cerebellar syndrome. METHODS: A cross-sectional study was conducted in 37 non-ataxic SCA2 mutation carriers and in age- and sex-matched healthy controls. All subjects underwent clinical assessment and transcranial magnetic stimulation to determine corticospinal...
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