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Article

Abnormal diffusion tensor in nonsymptomatic familial amyotrophic lateral sclerosis with a causative superoxide dismutase 1 mutation.

Journal of magnetic resonance imaging : JMRI - 1 Jan 2008

Ng Man-Cheuk, Ho Jenny Ting, Ho Shu-Leong, Lee Raymand, Li Geng, Cheng Tat-Sun, Song You-Qiang, Ho Philip Wing-Lok, Fong Gardian Chung-Yan, Mak Windsor, Chan Koon-Ho, Li Leonard Sheung-Wai, Luk Keith Dip-Kei, Hu Yong, Ramsden David Boyer, Leong Lilian Ling-Yee

Abstract excerpt

PURPOSE: To determine whether diffusion abnormalities can be observed in nonsymptomatic family members with a known causative Cu/Zn superoxide dismutase mutation (asymptomatic familial amyotrophic lateral sclerosis; AFALS(+SOD1)) in a family with autosomal dominant familial amyotrophic lateral sclerosis (ALS) using diffusion tensor imaging (DTI). MATERIALS AND METHODS: A total of eight AFALS(+SOD1) subjects (aged...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18022844
DOI: 10.1002/jmri.21217

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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