Article
Progression of corticospinal tract dysfunction in pre-ataxic spinocerebellar ataxia type 2: A two-years follow-up TMS study.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology - 1 May 2018
Velázquez-Pérez Luis, Rodríguez-Labrada Roberto, Torres-Vega Reidenis, Ortega-Sánchez Ricardo, Medrano-Montero Jacqueline, González-Piña Rigoberto, Vázquez-Mojena Yaimeé, Auburger Georg, Ziemann Ulf
Abstract excerpt
OBJECTIVE: Corticospinal tract (CST) dysfunction is common in the pre-ataxic stage of spinocerebellar ataxia type 2 (SCA2) but quantitative assessment of its progression over time has not been explored. The aim of this study was to quantify the progression of CST dysfunction in pre-ataxic SCA2 using transcranial magnetic stimulation (TMS). METHODS: Thirty-three pre-ataxic SCA2 mutation carriers and a 33 age- and...
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