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Article

Gene-gene interactions lead to higher risk for development of type 2 diabetes in an Ashkenazi Jewish population.

PloS one - 26 Mar 2010

Neuman Rosalind J, Wasson Jon, Atzmon Gil, Wainstein Julio, Yerushalmi Yair, Cohen Joseph, Barzilai Nir, Blech Ilana, Glaser Benjamin, Permutt M Alan

Abstract excerpt

BACKGROUND: Evidence has accumulated that multiple genetic and environmental factors play important roles in determining susceptibility to type 2 diabetes (T2D). Although variants from candidate genes have become prime targets for genetic analysis, few studies have considered their interplay. Our goal was to evaluate interactions among SNPs within genes frequently identified as associated with T2D....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20361036
DOI: 10.1371/journal.pone.0009903
PMCID: PMC2845632

Genes

WFS1
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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