Article
Evidence of interaction between type 2 diabetes susceptibility genes and dietary fat intake for adiposity and glucose homeostasis-related phenotypes.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2009
Ruchat Stephanie-May, Elks Cathy E, Loos Ruth J F, Vohl Marie-Claude, Weisnagel S John, Rankinen Tuomo, Bouchard Claude, Pérusse Louis
Abstract excerpt
BACKGROUND/AIMS: Genome-wide association studies have led to the identification of several susceptibility genes for type 2 diabetes mellitus (T2DM). The objective of this study was to test the hypothesis that the associations between single nucleotide polymorphisms (SNPs) in these genes and adiposity and glucose homeostasis-related phenotypes are influenced by dietary fat intake. METHODS: Thirty-three SNPs in 9...
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