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Article

Feasible and successful: genome-wide interaction analysis involving all 1.9 x 10(11) pair-wise interaction tests.

Human heredity - 1 Jan 2010

Steffens Michael, Becker Tim, Sander Thomas, Fimmers Rolf, Herold Christine, Holler Daniela A, Leu Costin, Herms Stefan, Cichon Sven, Bohn Bastian, Gerstner Thomas, Griebel Michael, Nöthen Markus M, Wienker Thomas F, Baur Max P

Abstract excerpt

The Genome-Wide Association Study (GWAS) is the study design of choice for detecting common genetic risk factors for multifactorial diseases. The performance of full Genome-Wide Interaction Analyses (GWIA) has always been considered computationally challenging. Two-stage strategies to reduce the amount of numerical analysis require the detection of single marker effects or prior pathophysiological hypotheses...

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PMID: 20357478
DOI: 10.1159/000295896

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CTNNA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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