Article
Efficiently finding genome-wide three-way gene interactions from transcript- and genotype-data.
Bioinformatics (Oxford, England) - 1 Nov 2009
Kayano Mitsunori, Takigawa Ichigaku, Shiga Motoki, Tsuda Koji, Mamitsuka Hiroshi
Abstract excerpt
MOTIVATION: We address the issue of finding a three-way gene interaction, i.e. two interacting genes in expression under the genotypes of another gene, given a dataset in which expressions and genotypes are measured at once for each individual. This issue can be a general, switching mechanism in expression of two genes, being controlled by categories of another gene, and finding this type of interaction can be a...
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