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Article

Novel Heterotypic Rox Sites for Combinatorial Dre Recombination Strategies.

G3 (Bethesda, Md.) - 29 Dec 2015

Chuang Katherine, Nguyen Eileen, Sergeev Yuri, Badea Tudor C

Abstract excerpt

Site-specific recombinases (SSRs) such as Cre are widely used in gene targeting and genetic approaches for cell labeling and manipulation. They mediate DNA strand exchange between two DNA molecules at dedicated recognition sites. Precise understanding of the Cre recombination mechanism, including the role of individual base pairs in its loxP target site, guided the generation of mutant lox sites that specifically...

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Identifiers

PMID: 26715092
DOI: 10.1534/g3.115.025841
PMCID: PMC4777119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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