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Article

4G/5G polymorphism and haplotypes of SERPINE1 in atherosclerotic diseases of coronary arteries.

Thrombosis and haemostasis - 1 Jun 2010

Koch Werner, Schrempf Matthias, Erl Anna, Mueller Jakob C, Hoppmann Petra, Schömig Albert, Kastrati Adnan

Abstract excerpt

We assessed the association between common variation at the SERPINE1 (PAI1) locus and myocardial infarction (MI). Haplotype-tagging polymorphisms, including the 4G/5G deletion/insertion polymorphism and seven single nucleotide polymorphisms, were analysed in a German sample containing 3,657 cases with MI and 1,211 controls. The association between the 4G/5G polymorphism and MI was examined in a meta-analysis of...

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Source

Identifiers

PMID: 20352162
DOI: 10.1160/TH09-10-0702

Genes

SERPINE1

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