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Article

Common variants in the haemostatic gene pathway contribute to risk of early-onset myocardial infarction in the Italian population.

Thrombosis and haemostasis - 1 Oct 2011

Guella Ilaria, Duga Stefano, Ardissino Diego, Merlini Pier Angelica, Peyvandi Flora, Mannucci Pier Mannuccio, Asselta Rosanna

Abstract excerpt

Occlusive coronary thrombus formation superimposed on an atherosclerotic plaque is the ultimate event leading to myocardial infarction (MI). Therefore, haemostatic proteins may represent important players in the pathogenesis of MI. It was the objective of this study to evaluate, in a comprehensive way, the role of haemostatic gene polymorphisms in predisposition to premature MI. A total of 810 single nucleotide...

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Identifiers

PMID: 21901231
DOI: 10.1160/TH11-04-0247

Genes

ITGA2
PLAT
PROCR
PROS1
SERPINE1
THBD
VWF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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