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Article

The association of PAI-1 promoter 4G/5G insertion/deletion polymorphism with myocardial infarction and stroke in young women.

Journal of cardiovascular risk - 1 Apr 2002

Hindorff Lucia A, Schwartz Stephen M, Siscovick David S, Psaty Bruce M, Longstreth W T, Reiner Alexander P

Abstract excerpt

BACKGROUND: The plasminogen activator inhibitor-1 (PAI-1) promoter 4G/5G insertion/deletion polymorphism has been associated with increased risk of myocardial infarction (MI) and decreased risk of cerebrovascular events. Whether these results apply to young women is not known. METHODS: We genotyped 78 MI cases, 106 stroke cases and 385 age-matched controls from a population-based case-control study of MI and...

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Source

Identifiers

PMID: 12006921
DOI: 10.1177/174182670200900209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The association of PAI-1 promoter 4G/5G insertion/deletion polymorphism with myocardial infarction and stroke in young women.PMID 12006921Read ↗

Reduced carriership of 4G allele of plasminogen activator inhibitor-1 4G/5G polymorphism in very young survivors of myocardial infarction.Semantic proximity Read ↗

Association of tissue plasminogen activator and plasminogen activator inhibitor polymorphism with myocardial infarction: a meta-analysis.Semantic proximity Read ↗

Plasminogen activator inhibitor 4G polymorphism is associated with decreased risk of cerebrovascular mortality in older women.Semantic proximity Read ↗

4G/4G genotype of PAI-1 gene is associated with reduced risk of stroke in elderly.Semantic proximity Read ↗

Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of ischemic stroke: a meta-analysis.Semantic proximity Read ↗

The 4G/4G genotype at nucleotide position -675 in the promotor region of the plasminogen activator inhibitor 1 (PAI-1) gene is less frequent in young patients with minor stroke than in controls.Semantic proximity Read ↗

Association of the plasminogen activator inhibitor-1 gene 4G/5G polymorphism with ST elevation acute myocardial infarction in young patients.Semantic proximity Read ↗

An effect of the PAI-1 4G/5G polymorphism on cholesterol levels may explain conflicting associations with myocardial infarction and stroke.Semantic proximity Read ↗

4G/5G promoter polymorphism of plasminogen activator inhibitor-1, lipid profiles, and ischemic stroke.Semantic proximity Read ↗

Plasminogen activator inhibitor-1 4G/5G promoter polymorphism and PAI-1 plasma levels in young patients with ischemic stroke.Semantic proximity Read ↗

The 4G4G genotype of the plasminogen activator inhibitor 4G/5G gene polymorphism is associated with coronary atherosclerosis in patients at high risk for this disease.Semantic proximity Read ↗

Plasminogen activator inhibitor type 1 gene polymorphisms and haplotypes are associated with plasma plasminogen activator inhibitor type 1 levels but not with myocardial infarction or stroke.Semantic proximity Read ↗

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