Article
Reduced carriership of 4G allele of plasminogen activator inhibitor-1 4G/5G polymorphism in very young survivors of myocardial infarction.
Journal of thrombosis and thrombolysis - 1 May 2010
Rallidis Loukianos S, Gialeraki Argyri, Merkouri Efrosyni, Liakos George, Dagres Nikolaos, Sionis Dimitrios, Travlou Anthi, Lekakis John, Kremastinos Dimitrios T
Abstract excerpt
There are limited and controversial data regarding the impact of 4G/5G polymorphism of the plasminogen activator inhibitor-1 (PAI-1) gene in the pathogenesis of premature myocardial infarction (MI). We explored whether 4G/5G polymorphism of the PAI-1 gene is associated with the development of MI <or= 35 years of age. We recruited 201 consecutive patients who had survived their first acute MI <or= 35 years of age...
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