Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of tissue plasminogen activator and plasminogen activator inhibitor polymorphism with myocardial infarction: a meta-analysis.

Thrombosis research - 1 Sept 2012

Gong Li-Li, Peng Jian-Hao, Han Fei-Fei, Zhu Jin, Fang Lian-Hua, Wang Yue-Hua, Du Guan-Hua, Wang He-Yao, Liu Li-Hong

Abstract excerpt

INTRODUCTION: To investigate whether t-PA Alu repeat insertion/deletion (I/D) and PAI-1 4G/5G genetic variations are associated with the risk of MI. METHODS: We conducted a meta-analysis to assess the association between the t-PA I/D and PAI-1 4G/5G polymorphisms and risk of MI. We also performed subgroup analyses based on ethnicity (Caucasian, Asian, and African), gender and age. Forty one eligible studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Distribution
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myocardial Infarction

Share to Polymorphism, Single Nucleotide

Share to Prevalence

Share to Risk Factors

Share to Sex Distribution

Share to Tissue Plasminogen Activator

Source

Identifiers

PMID: 22771216
DOI: 10.1016/j.thromres.2012.06.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of tissue plasminogen activator and plasminogen activator inhibitor polymorphism with myocardial infarction: a meta-analysis.PMID 22771216Read ↗

The association between plasminogen activator inhibitor type 1 (PAI-1) levels, PAI-1 4G/5G polymorphism, and myocardial infarction: a Mendelian randomization meta-analysis.Semantic proximity Read ↗

The association of PAI-1 promoter 4G/5G insertion/deletion polymorphism with myocardial infarction and stroke in young women.Semantic proximity Read ↗

Association of PAI-1 4G/5G and -844G/A gene polymorphisms and changes in PAI-1/tissue plasminogen activator levels in myocardial infarction: a case-control study.Semantic proximity Read ↗

Role of tissue plasminogen activator and plasminogen activator inhibitor polymorphism in myocardial infarction.Semantic proximity Read ↗

Relationship between gene polymorphism of the PAI-1 promoter and myocardial infarction.Semantic proximity Read ↗

Plasminogen Activator Inhibitor-1 Polymorphisms and Risk of Coronary Artery Disease: Evidence From Meta-Analysis and Trial Sequential Analysis.Semantic proximity Read ↗

The 4G/5G polymorphism of PAI-1 promoter gene and the risk of myocardial infarction: a meta-analysis.Semantic proximity Read ↗

Plasminogen activator inhibitor-1 4G/5G gene polymorphism and coronary artery disease in the Chinese Han population: a meta-analysis.Semantic proximity Read ↗

Plasminogen activator inhibitor-1 4G4G genotype is associated with myocardial infarction but not with stable coronary artery disease.Semantic proximity Read ↗

The 4G4G genotype of the plasminogen activator inhibitor 4G/5G gene polymorphism is associated with coronary atherosclerosis in patients at high risk for this disease.Semantic proximity Read ↗

PAI-1 4G/5G and ACE I/D gene polymorphisms and the occurrence of myocardial infarction in patients on intermittent dialysis.Semantic proximity Read ↗

Reduced carriership of 4G allele of plasminogen activator inhibitor-1 4G/5G polymorphism in very young survivors of myocardial infarction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.