Article
Association of the CTLA4 gene with Graves' disease in the Chinese Han population.
PloS one - 23 Mar 2010
Zhao Shuang-Xia, Pan Chun-Ming, Cao Huang-Ming, Han Bing, Shi Jing-Yi, Liang Jun, Gao Guan-Qi, Peng Yong-De, Su Qing, Chen Jia-Lun, Zhao Jia-Jun, Song Huai-Dong
Abstract excerpt
To determine whether genetic heterogeneity exists in patients with Graves' disease (GD), the cytotoxic T-lymphocyte associated 4 (CTLA-4) gene, which is implicated a susceptibility gene for GD by considerable genetic and immunological evidence, was used for association analysis in a Chinese Han cohort recruited from various geographic regions. Our association study for the SNPs in the CTLA4 gene in 2640 GD...
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