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Article

Lack of a genetic association between the CTLA-4 gene and Graves' disease in Koreans.

Thyroid : official journal of the American Thyroid Association - 1 Mar 2006

Cho Hyun-Jung, Chung Jae Hoon, Kim In Sook, Kim Hee-Jin, Cho Seung Hee, Ki Chang-Seok, Kim Jong-Won

Abstract excerpt

Graves' disease (GD) is a complex autoimmune thyroid disease with a strong genetic component. The cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) gene, which encodes a negative regulator of the T-lymphocyte immune response, has been reported to be associated and/or linked to GD. Therefore, in order to determine the contribution of CTLA-4 in GD in Koreans, we genotyped the five single nucleotide Polymorphisms...

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Identifiers

PMID: 16571085
DOI: 10.1089/thy.2006.16.237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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